Significats de white adipocyte en anglès

In this study we sought to clarify the molecular differences between human brown and white adipocyte progenitors cells.

Brown and white adipocytes have been shown to derive from different progenitors.

We conclude angiotensinogen expression in white adipocytes is regulated nutritionally in a tissue-specific manner.

The browning of the white adipocytes involved increased norepinephrine release from the sympathetic nervous system.

Interestingly, mature white adipocytes are integrated into several tissues.

We also demonstrated that miRNAs are essential for the browning of subcutaneous white adipocytes in vitro and in vivo.

Taken together, the data bring to light an intriguing divergence between white adipocytes of the mouse and other mammalian species.

Conclusions: This work uncovers novel pathways regulated by PGC-1 alpha and reveals that PPARalpha controls gene expression in human white adipocytes.

White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo.

Together with dWAT's dynamic responses to external stimuli, we established that dermal adipocytes are a distinct class of white adipocytes with high plasticity.

We hypothesized that 10E,12Z-CLA impairs lipid storage in adipose tissue by altering the lipid metabolism of white adipocytes.

It is still not fully understood whether these cells differentiate de novo from specific progenitor cells or if they transdifferentiate from mature white adipocytes.

PM20D1 is a candidate thermogenic enzyme in mouse fat, with its expression cold-induced and enriched in brown versus white adipocytes.